"Mistress of Spices”, as the name suggests, has a lot of comprehensive characters that initiates consideration of how Divakaruni has included complex characters in the novel with the essence of reality. Tilo, the mistress of spices and the protagonist of this novel heals and solves the troubles of the Indian community in Oakland with her power using spices in an appropriate potency. The characters in this novel struggle due to their immigration. This novel, “Mistress of Spices”, is a spectacular display of spicy lives of the characters seasoned with problems. Keywords: complex and comprehensive characters, essence of reality, protagonist, spicy lives etc.